ABSTRACT
KEY POINTS ■ Primary stroke prevention is the single most effective and widely applicable approach in the
management of high-risk patients. ■ Transient ischemic attack is associated with a high early risk (often within two days) of ischemic
stroke and represents a unique opportunity to intervene urgently. ■ Atrial fibrillation and severe carotid stenosis are associated with considerable stroke risk and
warrant specific treatments including anticoagulation (warfarin) and carotid endarterectomy in appropriate cases.
