ABSTRACT

Parkinson’s disease (PD) is a neurologic syndrome defined by a triad of motor

symptoms. However, the frequent co-occurrence of cognitive, affective, and

other neurobehavioral disturbance suggests a neuropsychiatric condition with

highly varied symptoms. Depression and anxiety disorders, cognitive impair-

ment, and psychosis have long been recognized in some individuals diagnosed

with PD (1). Other common, but less well studied, psychiatric manifestations

include apathy (2), impulse control disorders (ICDs) (a.k.a., hedonistic home-

ostatic dysregulation, dopamine dysregulation syndrome, or compulsive

behavior) (3), disorders of sleep and wakefulness (4), and pseudobulbar affect.