ABSTRACT

Deep brain stimulation (DBS) is a fairly recent surgical therapy for the treatment

of Parkinson’s disease (PD), having first won Food and Drug Administration

(FDA) approval in 1997 [for use in the thalamus; approval for use in the subthala-

mic nucleus (STN) came in 2001]. As a surgical procedure involving the brain,

DBS requires the ethical oversight that is applied to any surgery and the

additional scrutiny due to a novel procedure that affects brain function.

In addition, DBS is used most often on patients who are elderly, in whom

other treatments have failed or ceased to be effective, who may be cognitively

or affectively impaired, and who may have comorbidities.