ABSTRACT
Prognostic models are widely used in cancer for investigating patient outcome in relation to multiple patient and disease characteristics. Such a model may allow the (reasonably) reliable classification of patients into two or more groups with different prognoses. It may be of particular interest to identify patients with a good prognosis that adjuvant therapy would not be (cost-)beneficial, or a group with a poor prognosis that more aggressive adjuvant therapy would not be justified (1).
