ABSTRACT

Congestive heart failure (CHF) is commonly regarded as the “final common pathway” of

cardiovascular decline resulting from all forms of heart disease. Despite advances in the

prevention and treatment of many forms of cardiovascular disease, CHF continues to

exist as a major and, unfortunately, growing form of morbidity and mortality in the

United States and around the world. As myocardial function declines and systemic

compensatory systems are activated to support blood pressure and organ perfusion,

patients progress through increasingly severe stages of CHF, each with increasing

morbidity and mortality.