ABSTRACT
Justin M. S. Lee and Robin P. Choudhury Department of Cardiovascular Medicine, University of Oxford, John Radcliffe
Hospital, Oxford, U.K.
SUMMARY
lar events such as myocardial infarction and stroke. ■ Features of the syndrome including obesity, dyslipidemia, hypertension, and
hyperglycemia act synergistically to promote the development of atherosclerosis. ■ The mechanisms by which atherosclerosis is accelerated include impairment
of endothelial function and increased oxidative stress and inflammation, and thrombosis.
