ABSTRACT

Basic calcium phosphate (BCP) deposition disease encompasses clinical

syndromes caused by pathologic deposits of a variety of crystalline mineral

including octacalcium phosphate, tricalcium phosphate, and most often carbonate-

substituted apatite. If sufficient mineral deposits are present they can be detected

radiographically, but not specifically identified. Methods for specific identifica-

tion are detailed in Chapter 10, and include X-ray diffraction, Fourier transform

infrared spectroscopy, transmission and scanning electron microscopy with

energy dispersive analysis, and atomic force microscopy. These methods have

variable degrees of specificity and require varying quantities of mineral for

precise characterization.