ABSTRACT

Current transplant immunosuppression commonly entails one or more of a variety of agents (see Table 62.1). Calcineurin inhibitors (CNIs), antiproliferative agents, and corticosteroids are the most common medications used to maintain immune balance between the host and the graft. In the initial phase, there may also be supplemental “induction” therapy, usually with biological agents such as antilymphocyte agents or interleukin receptor blockers. Occasionally, adjunctive treatments like plasmapheresis are used.