ABSTRACT

Research, Enterprise, and Regional Affairs, University of Greenwich, London, U.K.

Ghassan F. Shattat

Health and Life Sciences Department, Coventry University, Coventry, U.K.

INTRODUCTION

The prevalence of cardiovascular diseases will undoubtedly increase as the mean age of the populations throughout the world increases. Heart disease is generally complex and multifactorial. Despite considerable advances in therapy, the understanding of the underlyingmechanisms are still rather poor. Efforts are being directed towards the development of new drugs through the modification of the physicochemical properties of drug molecules, and the design and synthesis of new drugs with particular emphasis on drug delivery systems, pharmaceutical materials research, controlled drug release and targeting of drugs to the site of action to enhance the therapeutic effects.