ABSTRACT
Chewing gum has been used worldwide since ancient times when man experienced the pleasure of chewing a variety of substances. Now, chewing gum is also used as a convenient modified-release drug delivery system. Commercially available medicated chewing gums are used for pain relief, smoking cessation, motion sickness, and freshening of the breath. In addition, a large number of chewing gums intended for caries prevention, xerostomia alleviation, tooth whitening, and vitamin/mineral supplementation are also on the market.
