ABSTRACT

Since Trousseau’s time, the strong clinical association between cancer and venous thromboembolism (VTE) has been frequently observed and documented, and cancer patients clearly exhibit a higher risk of developing a thrombotic event when compared to noncancer patients. The risk is substantial, particularly in the presence of well-known risk factors such as prolonged immobilization, surgery, and chemo-radio-hormonal therapy. VTE, especially in its idiopathic presentation, may represent an epiphenomenon of yet undisclosed cancer, offering possible chances for early diagnosis and treatment.