ABSTRACT

Image-guided Radiotherapy and Central Nervous System Lymphoma Primary central nervous system lymphoma (PCNSL) is a malignant non-Hodgkin’s lymphoma (NHL) arising in the central nervous system (CNS) [1]. is disease represents 3-7% of primary brain tumors [1,2]. Treatment strategies vary, but usually involve chemotherapy and whole brain radiation therapy (WBRT). Imaging (computed tomography [CT], magnetic resonance imaging [MRI], single-photon emission computed tomography [SPECT] and positron emission tomography [PET]) can aid in the diagnosis and guide treatment, and may also be useful in assessing a patient’s response to therapy and identifying tumor recurrences. Studies that have investigated the role of imaging with PCNSL are small, and newer modalities need further investigation.