ABSTRACT

Table 1 provides a list of RNA virus vectors discussed in this review.

VACCINE VECTORS DERIVED FROM POSITIVE STRAND RNA VIRUSES Propagation Competent Vectors Propagation competent vectors express an immunizing gene in the context of a complete virus genome. For instance, a second copy of an alphavirus subgenomic mRNA promoter can be inserted into the genome for expression of an immunizing transgene (5-9).