ABSTRACT

Coronary heart disease (CHD) is the central component of a broad spectrum of disease

conditions affecting the heart and circulation, collectively termed atherosclerotic cardiovas-

cular disease, that progress dramatically as age advances. Although CHD in all its clinical

manifestations contributes significantly to disability and death throughout life, its toll is

heaviest in the elderly (1-7). Because there is a substantial paucity of epidemiological

information regarding both the development and prevention of CHD in the elderly, a thorough

evaluation of the role of risk factors for CHD in older persons and the potential benefits of

their amelioration would represent an important contribution to the clinical and preventive

management of this disease in a large segment of the United States and world population.