ABSTRACT

In 2002, the US Environmental Protection Agency (EPA) issued the Interim Policy on Genomics that outlined the Agency’s initial approach to the use of genomics data and information in risk assessment and decision-making ( 1 ). The Interim Policy describes genomics as the study of all the genes of a cell or tissue, at the DNA (genotype), mRNA (transcriptome), or protein (proteome) level. The Interim Policy noted that genomics data and information might be considered in the EPA decision-making process, as part of the weight of the evidence on a case-by-case basis, but that these data alone are currently considered insuffi cient as a basis for the decisions.