ABSTRACT
INTRODUCTION Crohn’s Disease (CD) is a lifelong disorder of unknown etiology characterized by chronic focal, transmural, and granulomatosos inflammation that can affect any portion of the gastrointestinal tract. The transmural inflammation often leads to fibrosis and to obstructive clinical presentations. Crohn’s disease was first described by B. Crohn, L.Ginzburg, and G.Oppenheimer in 1932 as an inflammatory condition limited to the terminal ileum.(1) Later, Lockhart-Mummery and Morson (2) described granulomatous colitis, and the disease process was understood to potentially affect the large bowel. It can occur from the mouth through the anus. The clinical symptoms are related to the site of the disease. As it is more prevalent among the terminal ileum and right colon, the most frequently symptoms are: diarrhea, weight loss, abdominal pain, and perineal disease. But the clinical features indicate the site of the disease.(3)
a) Oral: Aphthous ulceration on the background of a mucosal edema is the most common oral manifestation of CD. Additional lesions described include: granulomatous masses, chelitis, and granulomatous sialadenitis. Lesions usually coexist with an intestinal disease.
