ABSTRACT

INTRODUCTION The molecular chirality associated with an optically active molecule is frequently manifested in the crystallography of the compound, and one often encounters a type of polymorphism between racemic mixtures and resolved enantiomers where the two species crystallize in different space groups (1) . Because the historical development of optical activity was greatly aided by systematic studies of the habits of enantiomorphic crystals, the concepts of molecular dissymmetry, crystallography, and chirality are inexorably linked. As with any other solid, these materials can be characterized on the basis of their crystal structures and through an understanding of their melting point phase diagrams.