ABSTRACT

Electron microscopy (EM) is an important adjunct to other diagnostic virology tests. In some cases, it may be the only procedure for detecting viruses because they are fastidious or not cultivable in the routine culture laboratory or because biochemical probes are not readily available. Even when biochemical tests for a virus exist, their selection and application require a preconceived notion of which viral agent(s) is present. Additionally, cross-reactions may give false-positive results.