ABSTRACT

SUMMARY The present chapter in this review work intends to give insight into elastomeric closures that are used for parenterals. The single most important reason why elastomeric materials are used for closures for parenterals is that the elasticity of such materials allows for preservation of the sterility of the packaged drug, by ensuring a tight seal between the closure and the container, and by ensuring adequate resealing of the closure after penetration with a needle or with a spike in cases where this is applicable.