ABSTRACT

INTRODUCTION Dry heat is one of the oldest methods of sterilization. Dry heat is used in the pharmaceutical industry mainly for depyrogenation of glassware and equipment going into an aseptic processing area. Because of the high heat required for the depyrogenation process, products that have been validated for depyrogenation are considered to be validated for sterilization without additional work (1). More limited use of dry heat processes are for sterilization alone.