ABSTRACT

Introduction The adult population is most commonly the “target group” of vascular sciences worldwide, with atherosclerosis being the predominant etiologic factor for vascular diseases. Chronic lower limb ischemia represents a large portion of the so-called “vascular patients” and is associated with increased morbidity and mortality. Walking disability, referred to as intermittent claudication (IC), is the most common clinical presentation and is associated not only with increased risk for amputation, but is also a marker of concomitant cardiovascular and cerebrovascular diseases and of limited life expectancy.1