Angiography and the vulnerable plaque John A Ambrose and Cezar S Staniloae

Caleb Hillier Parry, in his Inquiry into the Symptoms and Causes of the Syncope Anginosa, Commonly Called Angina Pectoris, Illustrated by Dissections (1799), recounts the classical anecdote in which, during the course of an autopsy, he discovered something hard and gritty in the coronary arteries. He noted that the vessels had hardened, or ossified, and later in the same book he states that, ‘a principal cause of the syncope anginosa is to be looked for in disordered coronary arteries.’