ABSTRACT

Despite efforts such as revascularization to halt the progression to ischemic heart failure, ventricular remodeling is still a growing danger. Efforts to treat severely compromised hearts refractory to medical therapy have included heart transplantation and mechanical ventricular assistance.1 Until now, cardiologists believed that beyond revascularization and medical therapy, the process of ischemic heart failure was irreversible because the heart lacked the capacity to renew itself.