ABSTRACT
The only way to achieve such a diagnosis would be to assess systematically the arterioventricular concordance in all fetuses at the time of sonographic examination, whatever the age of gestation or the indication. After more than 20 years of effort to obtain such care, prenatal diagnosis of transposition of the great arteries remains difficult to achieve. A wide range of diagnosis rates among surgical cardiopediatric neonates is currently observed: we note 7 % in 2004 at the Children ’ s Hospital Boston 1 compared with more than 65 % in Paris. 2
In contrast to most congenital heart malformations, transposition of the great arteries is considered to be isolated. It is largely accepted that neither family history nor sonographic signs pointing toward association, such as chromosomal anomalies including 22q11 deletion, are generally encountered, which excludes advice to systematically karyotype these fetuses. These assertions must be revisited.
