ABSTRACT

Structural development of human CNS All the neurons and glial cells originate from the embryonic ectoderm, precisely a structure called the neural plate. During the fourth postconceptional week, the neural plate bends into a neural tube, whose further growth reshaping and histological characteristics directly reflect complicated histogenetic processes. The results of those processes are specific transitional embryonic zones, which cannot be observed in an

adult brain. Three embryonic zones, ventricular, intermediary and marginal (seen from ventricular to pial surface), are present in all parts of the neural tube, whereas the telencephalon contains two additional zones, subventricular and subplate.1