ABSTRACT
In the last 20 years, concomitant with the development of intracytoplasmic sperm injection (ICSI), donor insemination (DI) has undergone a radical number of changes, for example, exclusive use of cryopreserved semen, removal of the anonymity of sperm donors, widespread development of commercial sperm banking, increasing treatment of single and lesbian women, changes in societies’ attitudes to the use of donor gametes-to name but a few. The purpose of this chapter is to discuss a number of these issues in the context of the history of DI and to look to the future of this treatment regimen.
