ABSTRACT

Wolffian ducts by stimulating the male internal genital development resulting in vas deferens, epididymis, and the seminal vesicles. AMH acts on the cells of the Mu¨llerian ducts, resulting in regression of these ducts and also preventing a formation of uterus and fallopian tubes. In the same manner, the external genital organs in males and females are identical until gestational week 6 (Fig. 1). Under the influence of high androgen levels locally in males, the genital tubercle grows and differentiates to a penis, the urethral plate gradually closes to a urethra that opens on the tip of the glans, a scrotum is formed by fusion in the midline, and the testes migrate from the initial abdominal position to the scrotum.