ABSTRACT
NOTE: EPA equivalent guidance is discussed within the body of this chapter can be found on the EPA website (www.epa.gov) OECD 407 Adopted: July 27,1995 Repeated Dose 28-day Oral Toxicity Study in Rodents OECD 414 Adopted: January 22, 2001 Proposal for Updating Guideline 414: Prenatal Develop-
mental Toxicity Study OECD 415 Adopted: May 26, 1983 One-Generation Reproduction Toxicity Study OECD 416 Adopted: January 22, 2001 Two-Generation Reproduction Toxicity Study OECD 421 Adopted: July 27, 1995 Reproduction/Developmental Toxicity Screening OECD 422 Adopted: March 22, 1996 Combined Repeated Dose Toxicity Study with the Repro-
duction/Developmental Toxicity Screening Test OECD 426 Adopted: October 16, 2007 Developmental Neurotoxicity Study OECD 440 Adopted: October 16, 2007 Uterotrophic Bioassay in Rodents: A short-term screening
test for estrogenic properties OECD 441 Adopted: September 7, 2009 Hershberger Bioassay in Rats: A short-term screening assay
for (anti) androgenic properties EPA OPPTS 890. Series .1450 Pubertal Development and Thyroid Function in Intact
Juvenile/Peripubertal Female Rats (October 2009) .1500 Pubertal Development and Thyroid Function in Intact
Juvenile/Peripubertal Male Rats (October 2009) NOTE: Since no exact equivalent currently exists in OECD
guidelines, the EPA guidelines have been included for pubertal (male and female) development and thyroid function.
