ABSTRACT
Maternal obesity results in in-utero programming and childhood obesity. Additionally, environmental factors such as diet play a role in obesity (55).
ETIOLOGY/BASIC PATHOPHYSIOLOGY White adipose tissue produces proteins with endocrine function called adipokines. A state of relative hypoxia occurs in the adipocytes in obesity, which sets a chronic inflammatory response, causing the release of adipokines. Leptin, adiponectin, resistin, and ghrelin are the most studied adipokines (56).
