ABSTRACT

Therapy Abrupt discontinuation of benzodiazepines may cause serious maternal withdrawal symptoms. Benzodiazepine withdrawal is less likely if a woman has not taken therapeutic doses (i.e., three to four times per day) for 4 weeks. These women should be reassessed for benzodiazepine withdrawal if they have changes in vital signs (systolic blood pressure 150 mmHg, diastolic blood pressure 100 mmHg, pulse >110 beats/min, temperature >1018F, or SpO2 <96%) or symptoms of anxiety or agitation.