ABSTRACT

Indications for pneumococcal vaccine are presented in Table 38.2. In pregnancy the evidence is often insufficient to get enough statistical power for effectiveness, but pneumococcal vaccination during pregnancy reduces the risk of neonatal infection (RR 0.51; 95% CI 0.18-1.41), and pneumococcal colonization in infants by 16 months of age (RR 0.33; 95% CI 0.11-0.98) (16).