ABSTRACT

Allergic contact dermatitis (ACD) is a type IV hypersensitivity reaction. Langerhans cells internalize the allergen and transport it through the lymphatic system to the lymph nodes where they present it to T lymphocytes and activate them. These activated T lymphocytes induce the infl ammatory reaction in the dermis. As for many other medications, there are cases of ACD from almost every group of ophthalmic drug. Here we want to give an overview of the reported cases and want to clarify, if there is an appropriate test to identify an allergic reaction caused by ophthalmics.