ABSTRACT
Polycystic ovary syndrome (PCOS) is a common polygenic multifactorial condition, affecting a wide population. Historically, the classic combination of symptoms was fi rst described in 1935 by Stein and Leventhal (1), who recognized that enlarged ovaries, amenorrhea, infertility, and hirsutism could be collated together. This collection of symptoms has been widely researched and many conclusions made, yet it continues to pose a diffi - cult condition to treat. PCOS is now recognized as a spectrum disorder ranging from ultrasound features of polycystic ovarian morphology (2) to anovulatory infertility. Obesity, hyperandrogenemia, and insulin resistance are all key factors that infl uence the expression and symptoms of the condition (3-5).
