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      Chapter

      Mining gene expression data
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      Chapter

      Mining gene expression data

      DOI link for Mining gene expression data

      Mining gene expression data book

      Mining gene expression data

      DOI link for Mining gene expression data

      Mining gene expression data book

      ByXiaohui Liu, Paul Kellam
      BookBioinformatics

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      Edition 1st Edition
      First Published 2002
      Imprint Taylor & Francis
      Pages 17
      eBook ISBN 9780203427828
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      ABSTRACT

      DNA microarray technology has enabled biologists to study all the genes within an entire organism to obtain a global view of gene interaction and regulation. This chapter introduces some of the most common data mining methods that are being applied to the analysis of microarray data and discusses the likely future directions. Data mining has been defined as the process of discovering knowledge or patterns hidden in datasets. The chapter presents some of the most commonly used methods for gene expression data exploration, including hierarchical clustering, K-means, and self-organizing maps (SOM). It describes that support vector machines (SVM) have become popular for classifying expression data, and the basic concepts of SVM. Different clustering algorithms may produce different clusters from the same data set. The global search and optimization methods such as genetic algorithms or simulated annealing can find the optimal solution to the square error criterion, and have already demonstrated certain advantages.

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