ABSTRACT

Serotonin (5–HT) has been suggested to play an important role in the control of aggressive behaviour in animals (Valzelli, 1981) and man (Muhlbauer, 1985). This does not imply, however, that serotonin is the most important neurotransmitter involved in aggression, because a number of other neurotransmitters have also been suggested to modulate aggressive behaviour, e.g. adrenaline and noradrenaline (Bell and Hepper, 1987; Eichelman 1987), acetylcholine (Bell et al., 1985), and GABA (Eichelman, 1987). Although multiple–transmitter modulation is more realistic for complex behaviours like aggression, serotonin may still play a key role although many aspects of its precise role still remain to be elucidated (Miczek, 1987; Olivier et al., 1987; Valzelli, 1984).