ABSTRACT
In 1981, together with colleagues Tsung-Yi Lin and Jonathan Fleming, we launched a long-term prospective study of schizophrenia by recruiting a large sample of individuals experiencing their first episode of psychosis. This study, which operated under the acronym MAP (for Markers and Predictors of schizophrenia), was concerned with how a number of different factors contribute to variability in the onset, presentation, and course of disorder in a cohort of 175 psychotic patients. Potential predictors selected for this study included specific clinical features and definitions of psychosis (Beiser, Fleming, Iacono, & Lin, 1988), psychophysiological markers (Iacono, 1985), anomalies in brain morphology, (Iacono, Smith, Moreau, Beiser, Fleming, Lin, & Flak, 1988), labeling by the self and significant others (Beiser, Waxier-Morrison, Iacono, Lin, Fleming, & Husted, 1987), life stress, role demands, coping abilities, and social support.
