ABSTRACT
Diagnosis .......................................................................................................... 180 Epidemiology ................................................................................................... 182 Age of Onset ..................................................................................................... 183 Gender and Race/Ethnicity ............................................................................. 184 Phenomenology ................................................................................................ 185
Core Features ............................................................................................... 185 Course and Impact on Functioning ................................................................ 186 Comorbidity ...................................................................................................... 188 Genetics and Neurobiology ............................................................................. 190 Neuropsychology ............................................................................................. 193 Treatment ......................................................................................................... 194
Pharmacotherapy ......................................................................................... 194 Psychotherapy .............................................................................................. 195
Prevention ........................................................................................................ 196 Conclusions ...................................................................................................... 197 References ........................................................................................................ 197
There has been a growing awareness that the onset of bipolar disorder (BD) is often in childhood or adolescence, even though the typical symptom picture of mood dysregulation in adolescence is in many ways dissimilar to the symptom picture in adults.