ABSTRACT

Research on the biological changes of adolescence has exploded in recent years, advancing our understanding of the role of genetic, neurobiological, hormonal, and sleep-related factors in adolescent depression (see Goodyer, this volume; Lau & Eley, this volume; Wolfson & Armitage, this volume). Similarly, our methods for studying psychosocial change in adolescence, and its impact on depression, have improved greatly, leading to a large research base (see Abela & Hankin, this volume; Compas, Jaser, & Benson, this volume; Hammen, this volume; Joormann, Eugène, & Gotlib, this volume; Rudolph, this volume). Finally, state-of-the-art methods for conducting randomized clinical trials have been used to assess a number of different intervention and prevention programs for adolescent depression in the last decade or so, to the point that meta-analyses of this research are possible (see Garber, Webb, & Horowitz, this volume; Gunlicks & Mufson, this volume; Kaslow, Broth, Cowles Arnette, & Collins, this volume; McLaughlin, this volume; Stark, Krumholz, Ridley, & Hamilton, this volume; Weersing & Gonzalez, this volume; Zalsman, Shoval, & Rotstein, this volume).