ABSTRACT
Preterm infants have a high prevalence of long-term cognitive and behavioral disturbances. This chapter measures regional brain volumes on the magnetic resonance imaging (MRI) scans of 25 prematurely born 8-year-old children and 39 group-matched term control children. It hypothesizes that brain volumes of the preterm children would differ significantly from volumes of the term controls and that these abnormalities would be regionally specific. It examines the associations of regional brain volume with cognitive measures to test our hypothesis that abnormalities in brain volume would be associated with deficits in long-term cognitive outcome. The chapter examines the associations between regional brain volume and perinatal risk factors in the preterm cohort.
