ABSTRACT

Allergic or hypersensitivity reactions can be elicited by antigens that are not associated with infectious agents, for example pollen, dust, food, and chemicals in the environment. They do not usually occur on the first encounter with the antigen, but a second or subsequent exposure of a sensitized individual causes an allergic reaction whose symptoms will depend on the type of antigen, the route by which it enters the body, and the cells involved in the immune response. These unwanted responses can cause distressing symptoms, tissue damage, and even death. These are the same reactions that would be provoked by a pathogenic antigen that behaved in the same way. When they are not helping to clear up an infection, however, these damaging side-effects are clearly unwanted.