The European project Sustainable Renovation of Buildings for Sustainable Neighbourhoods 1 combined research by ten European partners within fourteen municipal case studies. The project’s objective was to develop a new methodology with the necessary tools to promote sustainable development and quality of life at the crucial and challenging level of urban neighbourhoods. At its core HQE2R provides a decision support toolkit 2 for municipalities and their local partners, putting special emphasis on the aims of inhabitants and users of neighbourhoods. In its integrated approach, based on contributions from different national contexts, it is meant to be a framework generally applicable in Europe. The European partner municipalities of the project participated, on the one hand, to support the development of selected neighbourhoods towards sustainability. On the other hand, this opened up the opportunity for testing the methodology in different contexts and under different conditions.