The ﬁrst treatments for pathological gambling, as we have already pointed out, have been derived either from eﬀective treatments for other disorders, or from some intuition or very simple and basic supposition. They are, in general, unidirectional treatments, directed to modify one or two factors, considered determinant for the development of the dysfunction. We will only enumerate some of them, and consider more thoroughly those that at the present time are more interesting (see Table 14.4). At the moment the most interesting treatment programmes are the multiple-factor programmes, ambulatory applied. We will consider some of them next.