This chapter contributes to the theorizing of social ontology within the social sciences by taking an interdisciplinary stance (considering mainly anthropology and philosophy). It holds that embodied aspects of social realities in the global North are hegemonic and destructive, whereas differing social realities in the global South are oppressed. Therefore, social ontology is critically examined whether it could be a helpful tool, on the one hand, for a better (non-Eurocentric and global) understanding of social inequality and, on the other, for decolonizing the social sciences. It is suggested that, thoughtfully applied (multiple world thesis), social ontology as a theoretical concept might indeed provide emancipatory power for the global South against the destroying machine.