Human trafficking has been so strongly associated with the activities of organised crime that the terms have been described as ‘interchangeable’ and trafficking has been seen as one of the primary organised crime activities. M. C. Burke and R. Vayrynen have claimed that this kind of trafficking has been associated with transnational organised crime groups, small-organised criminal networks and local gangs involved in violations of labour and immigration laws, and government corruption. The increasing focus on both human trafficking and corruption is one outcome of important recent changes in the criminological landscape. Crimes with a transnational character and crimes of the powerful, particularly those perpetrated on the global south and those which engaged ‘the criminology of mobility’ began to assume increased importance. The chapter suggests that have reached a critical moment in the response to some of the most challenging offending which disfigures the contemporary global era.