The world clearly has become multipolar following the failure of the George W. Bush administration’s efforts to replace the bipolar power structure that collapsed in 1991 by a unipolar, United States (US)-centered system. The evolution of the US and Great Britain toward nationalism to some extent reflects unique circumstances in the Anglo-Saxon world. The general trend towards nationalism that has emerged within the Anglo-Saxon world is antithetical not only to the social market economy, but also to regional cooperation as such and the multiple multilateral approach of the continental European Union (EU). Although every democratic regional entity faces similar policy dilemmas, the case of the EU represents in some ways a unique policy paradox. In the EU’s experience, no autonomous socio-economic and cultural model is possible without a single currency. In spite of its unique situation and historical experiences, the EU might learn a few lessons from ASEAN.