ABSTRACT
Premature separation of rat pups from their dams greatly increases their susceptibility to restraint-induced gastric erosions that persists into adulthood. When prematurely separated female rats grow to adulthood and mate with stock males, their normally separated F1 progeny also have increased susceptibility to restraint-induced erosions. Cross-fostering studies showed that prenatal rather than postnatal factors transmit this susceptibility to the F1 progeny.
