This chapter brings new evidence on the relationship between short-term labour mobility, as proxied by tourism flows, and innovation in Africa. Using data from 34 African countries over the period 2011–2016 sourced from the World Bank’s Enterprise Survey, we find that short-term mobility positively contributes to innovation, making this a potentially effective channel for economic development alongside established determinants such as investments in R&D, foreign direct investments, and trade. Short-term labour mobility thus emerges in Africa, too, as a prospective policy lever to generate new productive knowledge and promote sustainable economic growth.