The Universal Design for Learning (UDL) approach has been introduced in Japan over the recent years. However, UDL-inspired initiatives have only begun to emerge in Japanese schools. In this chapter, the author introduces examples of UDL-based practices in Japanese ordinary schools where he has been working as a research collaborator. In addition, the author analyzes a case study of a student with autism spectrum disorder (ASD) who was enrolled in regular classes and examines the educational support provided to accommodate the student’s characteristics and needs. This chapter presents sound evidence that UDL can be incorporated in regular classes to aid students with various learning difficulties.