This chapter focuses on the needs of the intersex, those who are born with physiological characters of both male and female. Schools need to be made aware that there are natural physical variations on the normal male or female body that should be accepted, that there are many threads which constitute not only gender but humanness. Klinefelter Syndrome is probably the most common chromosomal variation found in humans. Many men have been evaluated and it has been found that the four most common conditions males with Klinefelter Syndrome may have are sterility, breast development, incomplete masculine body build, and social and/or school learning problems. The history of changes in the cultural definition not only of male or female but also of hermaphrodites helps to reinforce the mythic nature of sex and gender, even where essential criteria have been defined in terms of genitalia or reproductive capacity.