This chapter aims to describe the process of private company indebtedness in Mexico since 2006. Global policies promoting cheap money and increased liquidity worldwide have in effect also brought about the increased indebtedness of private companies in Mexico. The circumstances that have favoured indebtedness abroad are currently changing. A sample of 100 large companies registered with the Mexican Stock Exchange was examined in order to understand the changes prompted by growing indebtedness. The current development model has meant that in the present situation, large companies operating in Mexico have increased their indebtedness to an extraordinary extent. Global financial and monetary conditions, together with the need to expand Mexico’s financial system, given its scarce participation in the allocation of financing, have led to substantial changes in both the financial structure of large non-financial companies domiciled in Mexico and the sums involved.